Book Hotels in South Carolina Midlands, SC
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top South Carolina Midlands hotels
Cambria Hotel Columbia Downtown The Vista
1000 Lady Street Columbia SC
$127 nightly
The price is $142 total per night from Mar 15 to Mar 16
$142 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Room was spotless and very nice. I couldn’t hear anyone in the rooms around us. Staff was excellent, very friendly and helpful! There was no parking but valet took care of us!
Reviewed on Feb 14, 2026
Graduate by Hilton Columbia SC
1619 Pendleton Street Columbia SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $155 total per night from Mar 15 to Mar 16
$155 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in ...
The hotel was unique from lobby to room. Exceptionally clean and a fun place to stay.
Reviewed on Feb 13, 2026
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $108 total per night from Mar 1 to Mar 2
$108 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Room and bathroom was very clean. Breakfast was good as well
Reviewed on Feb 18, 2026
Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $86 total per night from Mar 22 to Mar 23
$86 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Staff was courteous. Hotel was very clean. Great amenities.
Reviewed on Feb 16, 2026
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
211 Lanneau Ct Columbia SC
Fully refundable
$99 nightly
The price is $110 total per night from Mar 22 to Mar 23
$110 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Staff was friendly; room was clean and quiet for the night; breakfast was good.
Reviewed on Feb 18, 2026
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$86 nightly
The price is $96 total per night from Mar 1 to Mar 2
$96 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
The Park Inn was nice enough and clean. But the slightly worn condition of some furniture would preclude a rating of 9.2. It probably should be slightly lower, around 8.9 - 9.0.
Reviewed on Feb 21, 2026
Sleep Inn Columbia
1901 Rockland Rd Columbia SC
Fully refundable
$84 nightly
The price is $91 total per night from Mar 15 to Mar 16
$91 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
The rooms are nice and clean an Miss Beth at front desk was amazing with customer service
Reviewed on Feb 16, 2026
Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr Columbia SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $99 total per night from Feb 23 to Feb 24
$99 total
Feb 23 - Feb 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies ...
Initially, I was in the outside room where the lock was not operable, but when I voiced my concern about my safety, the young lady that was on duty found me an inside room that was clean and very inviting
Reviewed on Feb 19, 2026
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Mar 21 to Mar 22
$89 total
Mar 21 - Mar 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Ok
Reviewed on Feb 18, 2026
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap South Carolina Midlands hotels
Econo Lodge Rock Hill Northeast
914 Riverview Rd Rock Hill SC
$45 nightly
The price is $50 total per night from Mar 21 to Mar 22
$50 total
Mar 21 - Mar 22
Total with taxes and fees
6/10 (878 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in South Carolina Midlands with star-rating
Check South Carolina Midlands Hotels by Star Rating
4 Star Hotels
6 properties
Recent South Carolina Midlands hotel reviews by fellow wanderers
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Staff was friendly; room was clean and quiet for the night; breakfast was good."
A verified traveler stayed at Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
Explore More Ways to Travel with Travelocity
- Hotels near Palmetto Health Heart Hospital
- Hotels near University of South Carolina
- Adults Only Resorts & in Lake Carolina
- Romantic Getaways & Hotels in Lake Carolina
- Lake Carolina Hotels
- Hotels near Oak Hills Golf Club
- Hotels near Hampton-Preston Mansion and Gardens
- Hotels near Segra Park
- Hotels with Suites in Shandon
- Shandon Hotels
- Beach Resorts & in Waverly
- Hotels with Suites in Waverly
- Waverly Hotels
- Hotels near Hilton Field
- Hotels near Village at Sandhill Mall
- Hotels near Palmetto Health Richland Hospital
- 4 Star Hotels in Elgin
- Apartments in Elgin
- B&B in Elgin
- Cabins in Elgin
- Condos in Elgin
- Extended Stay Hotels in Elgin
- Guest Houses in Elgin
- Elgin Hotels
- Motels in Elgin
- Vacation Homes in Elgin
- Apartments in Woodfield
- B&B in Woodfield
- Condos in Woodfield
- Cottages in Woodfield
- Woodfield Hotels
- Motels in Woodfield
- Downtown Columbia Hotels
- All Inclusive Resorts & in South Carolina
- Ski Resorts and in South Carolina
- Cabins in South Carolina
- Hotels near Sesquicentennial State Park
- Hotels near Palmetto Falls Water Park
- B&B in Dentsville
- Hotels with Bar in Dentsville
- Luxury Hotels in Dentsville
- Pet Friendly Hotels in Dentsville
- Dentsville Hotels
- Vacation Homes in Dentsville
- 4 Star Hotels in Blythewood
- 5 Star Hotels in Blythewood
- Apartments in Blythewood
- B&B in Blythewood
- Cabins in Blythewood
- Cottages in Blythewood
- Extended Stay Hotels in Blythewood
- Guest Houses in Blythewood
- Cheap Hotels in Blythewood
- Hotels with Hot Tubs in Blythewood
- Pet Friendly Hotels in Blythewood
- Spa Resorts & in Blythewood
- Hotel Wedding Venues Hotels in Blythewood
- Blythewood Hotels
- Motels in Blythewood
- Vacation Homes in Blythewood
- Extended Stay Hotels in Columbia
- Hotels with Hot Tubs in Columbia
- Luxury Hotels in Columbia
- Columbia Hotels
- Motels in Columbia
- Hotels near William Jennings Bryan Dorn Veterans Affairs Medical Center
- Old Shandon Hotels
- Hotels near Township Auditorium
- University Hill Hotels
- Hotels near Charlie W. Johnson Stadium
- Hotels near Allen University
- Hotels near Fort Jackson
- Apartments in Royal Pines Estates
- B&B in Royal Pines Estates
- Condos in Royal Pines Estates
- Guest Houses in Royal Pines Estates
- Hotels near Benedict College
- Hotels near Columbia Place Mall
- Hotels near Polo Road Ball Park
- Killian Hotels
